Keeping up with Protein Stable
Summarize the work and findings of the publication.
The change in Gibbs energy ∆G indicates whether a chemical reaction/process will occur spontaneously or not, with values equal to zero indicating that the system has reached equilibrium.
In this webinar, our Application Scientist, Dr Alastair Davy, will demonstrate the workflow for measuring the Gibbs Free Energy of proteins, using the SUPR-CM fluorescence plate reader.
Forced degradation studies are used routinely within biologic development including accelerated stability studies. They are also useful in understanding the stability of biologic on a more fundamental level.
The stability of a monoclonal antibody is quantified for different buffer solutions including MOPS, TRIS, sodium phosphate and sodium citrate. Read more.
